The New Generation of Platelet Additive Solution for Storage at 22 ̊C: Development and Current Experience

نویسندگان

  • Juergen Ringwald
  • Robert Zimmermann
  • Reinhold Eckstein
چکیده

The storage of platelets (PLTs) in PLT additive solutions (PASs) might have several advantages. It can reduce allergic and febrile transfusion reactions, facilitate AB0-incompatible PLT transfusions, enable pathogen inactivation, and make more plasma available for other purposes (eg, for fractionation). For this reason, there has been considerable focus on the development of new PASs that assure maintenance of good PLT quality throughout storage. Several compounds in PASs such as citrate, acetate, phosphate, potassium, and magnesium have all turned out to be important, and the same applies to the necessary amount of

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تاریخ انتشار 2006